Anticancer agent 182
Anticancer agent 182 (Compound 1) is a cytotoxic flavonoid compound isolated from the root ofMuntingia colabura L. Anticancer agent 182 exhibits anticancer activity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 133342-90-2
- Fòrmula: C18H20O5
- Peso molecular:316.35
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BC1 cell line | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human BC1 cells
Cytotoxicity against human BC1 cells
|
[PMID: 2045815] |
| Col2 | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human Col2 cells
Cytotoxicity against human Col2 cells
|
[PMID: 2045815] |
| HT-1080 | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human HT1080 cells
Cytotoxicity against human HT1080 cells
|
[PMID: 2045815] |
| KB | ED50 |
13.3 μg/mL
Compound: 1
|
Cytotoxicity against vincristine-resistant human KB cells
Cytotoxicity against vincristine-resistant human KB cells
|
[PMID: 2045815] |
| KB | ED50 |
9.4 μg/mL
Compound: 1
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 2045815] |
| Lu1 | ED50 |
>20 μg/mL
Compound: 1
|
Cytotoxicity against human Lu1 cells
Cytotoxicity against human Lu1 cells
|
[PMID: 2045815] |
| P388 | ED50 |
5.9 μg/mL
Compound: 1
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 2045815] |
| SK-MEL-2 | ED50 |
14.6 μg/mL
Compound: 1
|
Cytotoxicity against human SK-MEL-2 cells
Cytotoxicity against human SK-MEL-2 cells
|
[PMID: 2045815] |
Chemical Information
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No. CAS 133342-90-2
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Peso molecular 316.35
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Fòrmula C18H20O5
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SMILES
OC1=CC([C@@H]2CCC3=CC=C(OC)C=C3O2)=CC(OC)=C1OC
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)