ATB-343
ATB-343 is a derivative of Indomethacin that releases H2S. H2S has cytoprotective and anti-inflammatory effects, inhibiting leukocyte adhesion to vascular endothelium and leukocyte migration to inflammatory sites. ATB-343 can be used to suppress respiratory infections.
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- No. CAS: 1000700-26-4
- Fòrmula: C28H20ClNO4S3
- Peso molecular:566.11
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
3294.4 μM
Compound: 15
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Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
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[PMID: 28646655] |
| L02 | IC50 |
337.2 μM
Compound: 15
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Cytotoxicity against human LO2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
Cytotoxicity against human LO2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
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[PMID: 28646655] |
Chemical Information
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No. CAS 1000700-26-4
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Peso molecular 566.11
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Fòrmula C28H20ClNO4S3
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SMILES
O=C(CC1=C(C)N(C(C2=CC=C(C=C2)Cl)=O)C3=C1C=C(C=C3)OC)OC4=CC=C(C(SS5)=CC5=S)C=C4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATB-343 Related Classifications
HY-15033 Related Classifications
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