B 746
B746 is a clofazimine analog with anti-Mycobacterium avium complex (MAC) activity and is less effective when used with clofazimine or streptomycin.
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- No. CAS: 103051-26-9
- Fòrmula: C26H20Cl2N4
- Peso molecular:459.37
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vitro
B746 (1, 3, 10 μM; 7 days) significantly inhibits the growth of mycobacteria[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:beige mice
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Dosage:10, 20, 30 mg/kg
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Administration:p.o.; 10, 20, 30 mg/kg; single dose; first day and 2, 4 and 6 week after infection
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Result:Reduced Colony Forming Units (CFU) counts of Mycobacteria in spleen of beige mice.
Chemical Information
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No. CAS 103051-26-9
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Peso molecular 459.37
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Fòrmula C26H20Cl2N4
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SMILES
CC/N=C1C=C2N(C3=C(N=C2C=C\1NC4=CC=C(C=C4)Cl)C=CC=C3)C5=CC=C(C=C5)Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
B 746 Related Classifications
HY-113729 Related Classifications
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