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Referencia número: HY-128126

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B-TPMF

Name: B-TPMF
Brand: MedChemExpress
SKU: HY-128126
Price: 544.00 USD
Availability: InStock
Rating: 5 (1 reviews)

B-TPMF is a selective inhibitor of the KCa2.1 channel, with an IC₅₀ of 30 nM, and it has a competitive functional interaction with CM-TPMF.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 477865-65-9
Fòrmula: C₁₉H₂₄N₆O₂
Peso molecular:368.43

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

B-TPMF Chemical Structure

No. CAS: 477865-65-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

B-TPMF is a selective inhibitor of the KCa2.1 channel, with an IC₅₀ of 30 nM, and it has a competitive functional interaction with CM-TPMF^[1].

Chemical Information

No. CAS 477865-65-9
Peso molecular 368.43
Fòrmula C₁₉H₂₄N₆O₂
SMILES

CON/C=N/C1=NN2C(C(OC3=CC=C(C(C)(C)C)C=C3)C)=CC=NC2=N1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocolo

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Charlotte Hougaard, et al. Evidence for a common pharmacological interaction site on K(Ca)2 channels providing both selective activation and selective inhibition of the human K(Ca)2.1 subtype. Mol Pharmacol. 2012 Feb;81(2):210-9. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculadora de dilución

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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