BigLEN(mouse)
Based on 1 Customer Validation
BigLEN(mouse) is a potent and selective agonist of orphan G protein-coupled receptor 171 (GPR171), with a Kd of ∼0.5 nM. BigLEN(mouse) can be used to regulate responses associated with food intake and metabolism.
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- Pureza: 99.90%
- No. CAS: 501036-69-7
- Fòrmula: C78H130N24O22
- Peso molecular:1756.01
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Almacenamiento:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Kd: ∼0.5 nM (GPR171)[1]
Chemical Information
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No. CAS 501036-69-7
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Appearance Solid
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Peso molecular 1756.01
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Fòrmula C78H130N24O22
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Color White to off-white
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Sequence Shortening
LENPSPQAPARRLLPP
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvente y solubilidad
H2O : 100 mg/mL (56.95 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Gomes I, et, al. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16211-6. [Content Brief]
[2]. Mack SM, et, al. Neuropeptide PEN and Its Receptor GPR83: Distribution, Signaling, and Regulation. ACS Chem Neurosci. 2019 Apr 17;10(4):1884-1891. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.5695 mL | 2.8474 mL | 5.6947 mL | 14.2368 mL |
| 5 mM | 0.1139 mL | 0.5695 mL | 1.1389 mL | 2.8474 mL | |
| 10 mM | 0.0569 mL | 0.2847 mL | 0.5695 mL | 1.4237 mL | |
| 15 mM | 0.0380 mL | 0.1898 mL | 0.3796 mL | 0.9491 mL | |
| 20 mM | 0.0285 mL | 0.1424 mL | 0.2847 mL | 0.7118 mL | |
| 25 mM | 0.0228 mL | 0.1139 mL | 0.2278 mL | 0.5695 mL | |
| 30 mM | 0.0190 mL | 0.0949 mL | 0.1898 mL | 0.4746 mL | |
| 40 mM | 0.0142 mL | 0.0712 mL | 0.1424 mL | 0.3559 mL | |
| 50 mM | 0.0114 mL | 0.0569 mL | 0.1139 mL | 0.2847 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
BigLEN(mouse) Related Classifications
HY-P2210 Related Classifications
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