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Referencia número: HY-117457

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BPIC

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals.

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No. CAS: 1444382-92-6
Fòrmula: C₂₇H₂₀N₂O₅
Peso molecular:452.46

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

BPIC Chemical Structure

No. CAS: 1444382-92-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals^[1].

Ver todos los productos específicos de isoformas DNA/RNA Synthesis :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
CCRF S-180	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HeLa	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HepG2	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HL-60	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HT-29	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
K562	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
SH-SY5Y	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]

Chemical Information

No. CAS 1444382-92-6
Peso molecular 452.46
Fòrmula C₂₇H₂₀N₂O₅
SMILES

O=C(C1=C(O)C=CC(C2=NC(C(OCC3=CC=CC=C3)=O)=CC4=C2NC5=C4C=CC=C5)=C1)OC
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Shan Li, et al. BPIC: A novel anti-tumor lead capable of inhibiting inflammation and scavenging free radicals. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1146-50. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Actividad biológica
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BPIC

Ver todos los productos específicos de isoformas DNA/RNA Synthesis

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

BPIC Related Classifications

HY-117457 Related Classifications