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United States

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Referencia número: HY-178233

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CAT335

CAT335 is a TREK activator. CAT335 selectively and irreversibly activates TREK-1^CG∗. CAT335 can be used in the research of pain sensation, sleep, and intraocular pressure.

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No. CAS: 3032789-44-6
Fòrmula: C₁₈H₁₂Cl₂N₂O₃
Peso molecular:375.21

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

CAT335 Chemical Structure

No. CAS: 3032789-44-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

CAT335 is a TREK activator. CAT335 selectively and irreversibly activates TREK-1^CG∗. CAT335 can be used in the research of pain sensation, sleep, and intraocular pressure^[1].

Chemical Information

No. CAS 3032789-44-6
Peso molecular 375.21
Fòrmula C₁₈H₁₂Cl₂N₂O₃
SMILES

O=C1C=CC(N1C2=CC=C(C(NCC3=CC=C(C=C3Cl)Cl)=O)C=C2)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Adam R. RENSLO, et al. Covalent, chemogenetic activators for k2p potassium channels and uses thereof. WO2024064923A2. WIPO (PCT). 2023-09-22.

[2]. Deal PE, et al. Development of covalent chemogenetic K2P channel activators. Cell Chem Biol. 2024 Jul 18;31(7):1305-1323.e9. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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