CP-100356

9 Cited Publications
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Based on 9 publication(s) in Google Scholar

CP-100356 is an orally active dual MDR1 (P-gp)/BCRP inhibitor, with an IC50s of 0.5 and 1.5 µM for inhibiting MDR1-mediated Calcein-AM transport and BCRP-mediated Prazosin transport, respectively. CP-100356 is also a weak inhibitor of OATP1B1 (IC50 = ∼66 µM). CP-100356 is devoid of inhibition against MRP2 and major human P450 enzymes (IC50 > 15 µM).

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  • No. CAS: 142716-85-6
  • Fòrmula: C31H36N4O6
  • Peso molecular:560.64
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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