CP-424174
Based on 1 Customer Validation
CP-424174 is a reversible inhibitor against IL-1β processing with an IC50 of 210 nM.CP-424174 indirectly inhibits NLRP3.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.69%
- No. CAS: 210825-31-3
- Fòrmula: C22H29ClN2O4S
- Peso molecular:452.99
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Chemical Information
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No. CAS 210825-31-3
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Appearance Solid
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Peso molecular 452.99
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Fòrmula C22H29ClN2O4S
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Color White to off-white
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SMILES
O=S(C1=CC=CC(C(O)(C)C)=C1)(NC(NC2=C(C=C(C=C2C(C)C)Cl)C(C)C)=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 125 mg/mL (275.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureza y Documentación
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Ficha de datos (267 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Portuguese - PT (254 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2076 mL | 11.0378 mL | 22.0755 mL | 55.1889 mL |
| 5 mM | 0.4415 mL | 2.2076 mL | 4.4151 mL | 11.0378 mL | |
| 10 mM | 0.2208 mL | 1.1038 mL | 2.2076 mL | 5.5189 mL | |
| 15 mM | 0.1472 mL | 0.7359 mL | 1.4717 mL | 3.6793 mL | |
| 20 mM | 0.1104 mL | 0.5519 mL | 1.1038 mL | 2.7594 mL | |
| 25 mM | 0.0883 mL | 0.4415 mL | 0.8830 mL | 2.2076 mL | |
| 30 mM | 0.0736 mL | 0.3679 mL | 0.7359 mL | 1.8396 mL | |
| 40 mM | 0.0552 mL | 0.2759 mL | 0.5519 mL | 1.3797 mL | |
| 50 mM | 0.0442 mL | 0.2208 mL | 0.4415 mL | 1.1038 mL | |
| 60 mM | 0.0368 mL | 0.1840 mL | 0.3679 mL | 0.9198 mL | |
| 80 mM | 0.0276 mL | 0.1380 mL | 0.2759 mL | 0.6899 mL | |
| 100 mM | 0.0221 mL | 0.1104 mL | 0.2208 mL | 0.5519 mL |
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