CP-615003
CP-615003 is a potent and subtype-selective partial agonist of GABAA receptor (GABAA receptor) (Ki = 1.1 μM). CP-615003 is mainly converted into the active metabolite CP-900725 through oxidative deamination in monkeys and humans, and the latter also has GABAA receptor affinity. CP-615003 is a substrate of P-glycoprotein (P-gp/MDR1), resulting in severe limitation of its penetration into the central nervous system (CNS). CP-615003 can be used for the study of CNS-related indications.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 329016-45-7
- Fòrmula: C20H24FN3O3
- Peso molecular:373.42
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
Chemical Information
-
No. CAS 329016-45-7
-
Peso molecular 373.42
-
Fòrmula C20H24FN3O3
-
SMILES
O=C(C1=CNC2=C1C(CCC2)=O)NC3=CC=C(C(F)=C3)OCCNCCC
-
Synonyms
NGD-913
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CP-615003 Related Classifications
HY-165444 Related Classifications
Powered by Bioz
Keywords
- CP-615003
- 329016-45-7
- NGD-913
- CP615003
- CP 615003
- NGD913
- NGD 913
- GABA Receptor
- Gamma-aminobutyric acid Receptor
- γ-Aminobutyric acid Receptor
- P-glycoprotein (P-gp)
- CNS penetration
- cerebrospinal fluid (CSF)
- brain extracellular fluid (ECF)
- multidrug resistance protein 1 (MDR1)
- pharmacokinetics
- receptor occupancy projection
- Inhibitor
- inhibitor
- inhibit