Dendroside D
Dendroside D is a sesquiterpenoid compound. Dendroside D binds to the RNA site of RNA-dependent RNA polymerase and the active site of SARS-CoV-2 main protease through hydrogen bonds, electrostatic interactions, and hydrophobic interactions, thereby blocking viral replication. Dendroside D stimulates the proliferation of mouse T and B lymphocytes, promotes T and B lymphocyte proliferation, and exhibits immunomodulatory activity. Dendroside D can be used for viral infection and immune-related research.
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- No. CAS: 503443-09-2
- Fòrmula: C27H44O14
- Peso molecular:592.64
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
In Vitro
Dendroside D (15 mg; 7 days) is a glycoside that yields aglycone 1a and glucose upon enzymatic hydrolysis with β-cellulase[2].
The sugar moiety of Dendroside D (0.04 M; 1 h) is D-glucose, as confirmed by GLC retention time matching authentic D-glucose[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 503443-09-2
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Peso molecular 592.64
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Fòrmula C27H44O14
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SMILES
C(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)(=O)[C@@]2(C)[C@@]3([C@]2(CC[C@](CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)(O)[C@@]5([C@]3([C@H](C)CC5)[H])[H])[H])[H]
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dendroside D Related Classifications
HY-N21759 Related Classifications
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Keywords
- Dendroside D
- 503443-09-2
- Endogenous Metabolite
- DNA/RNA Synthesis
- Lipinski's rule of five
- hyaluronidase inhibitor
- COVID-19
- SARS-CoV-2 main protease active site
- RNA-dependent RNA polymerase RNA site
- molecular docking model
- SARS-CoV-2
- sesquiterpene guaiane group compound
- mouse T and B lymphocyte proliferation
- HAase catalytic site
- Inhibitor
- inhibitor
- inhibit