FR260330
FR260330 is a selective, orally active inhibitor for inducible nitric oxide synthase (iNOS) through suppression of iNOS dimerization. FR260330 inhibits the NO accumulation in rat splenocytes and human DLD-110 cells, with IC50 of 27 and 10 nM. FR260330 ameliorates the Lipopolysaccharides (HY-D1056)-induced inflammatory diseases in rats model.
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- No. CAS: 442198-67-6
- Fòrmula: C29H28ClF3N6O4
- Peso molecular:617.02
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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iNOS |
Chemical Information
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No. CAS 442198-67-6
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Peso molecular 617.02
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Fòrmula C29H28ClF3N6O4
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SMILES
O=C(N1CCC(OC2=NC=NC(C(F)(F)F)=C2)CC1)CNC([C@@H](NC(/C=C/C3=CC=C(Cl)C=C3)=O)CC4=CC=CC=N4)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FR260330 Related Classifications
HY-122063 Related Classifications
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