Furylfuramide
Furylfuramide is a food preservative that exhibits mutagenic activity. Furylfuramide can be degraded through the aerobic metabolism by liver microsomes.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3688-53-7
- Fòrmula: C11H8N2O5
- Peso molecular:248.19
-
Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Protocolo
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
Chemical Information
-
No. CAS 3688-53-7
-
Appearance Solid
-
Peso molecular 248.19
-
Fòrmula C11H8N2O5
-
Color Orange to red
-
SMILES
O=C(/C(C1=CC=CO1)=C/C2=CC=C(O2)[N+]([O-])=O)N
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Protocolo
-
Genotoxicity/Mutagenicity Study
The bacterial reverse mutation assay detects point mutations that restore amino-acid prototrophy in auxotrophic Salmonella typhimurium or Escherichia coli tester strains; after exposure to a test article, mutagenic activity is read out as an increased number of revertant colonies on minimal agar compared with the vehicle control. The assay uses tester strains with different mutation targets so that base-substitution and frameshift mutagens can be detected, and testing is performed with and without exogenous mammalian metabolic activation because some chemicals require biotransformation to become mutagenic.
Pureza y Documentación
-
Ficha de datos (268 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
[1]. Tazima Y, et, al. Mutagenicity of nitrofuran derivatives, including furylfuramide, a food preservative. Mutat Res. 1975;32(1):55-80. [Content Brief]
[2]. Shimada T, et, al. Metabolic deactivation of furylfuramide by cytochrome P450 in human and rat liver microsomes. Carcinogenesis. 1990 Jan;11(1):103-10. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Furylfuramide Related Classifications
HY-119669 Related Classifications
Powered by Bioz