Iberdomide (Standard)
Iberdomide (Standard) is the analytical standard of Iberdomide. This product is intended for research and analytical applications. Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 of ~150 nM for cereblon-binding affinity. Iberdomide, a derivative of Thalidomide (HY-14658), has antitumor and immunostimulatory activities.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98%
- No. CAS: 1323403-33-3
- Fòrmula: C25H27N3O5
- Peso molecular:449.50
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureza y Documentación
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Help & FAQs
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HY-101291
IberdomideCELMoD -
HY-A0003
LenalidomideImmunomodulator -
HY-10984
PomalidomideImmunomodulatory Agent -
HY-14658
ThalidomideCereblon Inhibitor -
HY-101488
CC-885CRBN Modulator/GSPT1 Molecular Glue Degrader -
HY-A0003R
Lenalidomide (Standard)Reference Standard -
HY-129395
MezigdomideCereblon E3 Ubiquitin Ligase Modulating Agent -
HY-100487
TAK-243UAE/E1 Inhibitor -
HY-100507
AvadomideCereblon Modulator -
HY-14658R
Thalidomide (Standard)Cereblon Inhibitor -
HY-114166
2-D08Sumoylation Inhibitor -
HY-19817
PRT4165E1/E2/E3 Enzyme Inhibitor
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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No. CAS 1323403-33-3
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Peso molecular 449.50
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Fòrmula C25H27N3O5
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SMILES
O=C([C@@H](N(CC1=C2C=CC=C1OCC3=CC=C(CN4CCOCC4)C=C3)C2=O)CC5)NC5=O
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Synonyms
CC-220 (Standard)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Chad C Bjorklund, et al. Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide- and pomalidomide-resistant multiple myeloma cells with dysregulated CRBN. Leukemia. 2020 Apr;34(4):1197-1201. [Content Brief]
[2]. Erin W Meermeier, et al. Tumor burden limits bispecific antibody efficacy through T cell exhaustion averted by concurrent cytotoxic therapy. Blood Cancer Discov. 2021 Jul;2(4):354-369. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Iberdomide (Standard) Related Classifications
HY-101291R Related Classifications
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