Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide- and pomalidomide-resistant multiple myeloma cells with dysregulated CRBN

  • Leukemia. 2020 Apr;34(4):1197-1201. doi: 10.1038/s41375-019-0620-8.
Chad C Bjorklund  1 ,  Jian Kang  1 ,  Michael Amatangelo  1 ,  Ann Polonskaia  1 ,  Mark Katz  1 ,  Hsiling Chiu  1 ,  Suzana Couto  2 ,  Maria Wang  2 ,  Yan Ren  2 ,  Maria Ortiz  3 ,  Fadi Towfic  1 ,  J Erin Flynt  1 ,  William Pierceall  1 ,  Anjan Thakurta  4
Affiliations
  • 1. Celgene Corporation, Summit, NJ, USA.
  • 2. Celgene Corporation, San Diego, CA, USA.
  • 3. Celgene Corporation, CITRE, Sevilla, Spain.
  • 4. Celgene Corporation, Summit, NJ, USA. [email protected].
PMID: 31719682 DOI: 10.1038/s41375-019-0620-8
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