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Referencia número: HY-15499

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K-832

K-832 is an orally active IL-1β secretion inhibitor. K-832 can be used in the research of rheumatoid arthritis.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 225666-85-3
Fòrmula: C₂₄H₁₉ClN₂OS
Peso molecular:418.94

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

K-832 Chemical Structure

No. CAS: 225666-85-3

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Actividad biológica

Descripciòn

K-832 is an orally active IL-1β secretion inhibitor. K-832 can be used in the research of rheumatoid arthritis^[1]^[2].

IC₅₀ & Target^[1]^[2]

IL-1β

Ver todos los productos específicos de isoformas Interleukin Related :

Chemical Information

No. CAS 225666-85-3
Peso molecular 418.94
Fòrmula C₂₄H₁₉ClN₂OS
SMILES

O=C1C=C(C2=CC=C(Cl)C=C2)C(C3=CC=C(SC)C=C3)=NN1CC4=CC=CC=C4
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Dumont F J. The interleukin-1 families of cytokines and receptors: therapeutic potential for immunomodulation and the treatment of inflammatory disorders. Expert Opinion on Therapeutic Patents, 2006, 16(7): 879-912.

[2]. Halim S A, et al. Attempt to explore the binding mechanism of IL-1β inhibitors via molecular docking studies. Med. Chem, 2015, 5(10): 452-457.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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K-832

Ver todos los productos específicos de isoformas Interleukin Related