M 16209
M 16209 is an orally active aldose reductase (AR) inhibitor. M 16209 inhibits partially purified AR from various sources with IC50 values of 0.12, 0.24, 4.5, 1.2 and 9.3 μM for rat lens AR, bovine lens AR, bovine kidney AR, canine lens AR and human placental AR. M 16209 can be used for the research of metabolic disease, such as diabetes.
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- No. CAS: 128851-36-5
- Fòrmula: C11H7BrN2O5S
- Peso molecular:359.15
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
M 16209 (10-30 mg/kg, p.o., daily for 14 days) ameliorates motor nerve conduction velocity delay in male Wistar rats with Streptozotocin (HY-13753)-induced diabetic neuropathy[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 128851-36-5
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Peso molecular 359.15
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Fòrmula C11H7BrN2O5S
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SMILES
O=C1NC(CN1S(=O)(C2=C(Br)C3=CC=CC=C3O2)=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
M 16209 Related Classifications
HY-101555 Related Classifications
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