Mitorubrin
Mitorubrin ((-)-Mitorubrin) is a compound that can be isolated from Penicillium purpurogenum JS03-21. Mitorubrin shows no significant inhibitory activity against the H1N1 influenza virus (IC50 > 200 μM).
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- No. CAS: 3403-71-2
- Fòrmula: C21H18O7
- Peso molecular:382.36
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDCK | IC50 |
>200 μM
Compound: 8
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Antiviral activity against Influenza A virus H1N1 infected in MDCK cells assessed as compound concentration required for inhibiting influenza virus yield at 48 h post-infection by crystal violet staining based CPE inhibition assay
Antiviral activity against Influenza A virus H1N1 infected in MDCK cells assessed as compound concentration required for inhibiting influenza virus yield at 48 h post-infection by crystal violet staining based CPE inhibition assay
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[PMID: 21879714] |
Chemical Information
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No. CAS 3403-71-2
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Peso molecular 382.36
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Fòrmula C21H18O7
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SMILES
O=C1C2=COC(/C=C/C)=CC2=CC([C@@]1(C)OC(C3=C(C=C(C=C3O)O)C)=O)=O
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Synonyms
(-)-Mitorubrin
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Structure Classification
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Initial Source
Penicillium purpurogenum
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mitorubrin Related Classifications
HY-N16425 Related Classifications
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