MK-3577
MK-3577 is an orally effective glucagon receptor (GCGR) antagonist that reduces hepatic glucose production and lowers blood glucose levels by blocking glucagon receptors on target organs, primarily the liver. Pharmacokinetic analysis in domestic cats indicates that MK-3577 reaches peak levels 3 to 4 hours after oral administration, with a half-life of approximately 15 hours. MK-3577 can be used in diabetes research.
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- No. CAS: 1019112-29-8
- Fòrmula: C30H30ClFN2O3
- Peso molecular:521.02
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 1019112-29-8
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Peso molecular 521.02
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Fòrmula C30H30ClFN2O3
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SMILES
CCC[C@H](C1=CC=C(C=C1)C(NCCC(O)=O)=O)[C@H](C2=CC=C(C=C2)Cl)C(C3=CC(C)=C4)=CNC3=C4F
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MK-3577 Related Classifications
HY-107129 Related Classifications
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