ML358
Based on 1 publication(s) in Google Scholar
ML358 is a first in class, potent, and selective inhibitor of the SKN-1 pathway (IC50=0.24 μM). ML358 sensitizes the model nematode C. elegans to oxidants and anthelmintic. ML358 potentially used as adjuvants to increase the efficacy and useful life of current anthelmintics.
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- No. CAS: 1158607-44-3
- Fòrmula: C21H26Cl3NO2
- Peso molecular:430.80
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) ML358
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Actividad biológica
IC50: 0.24 μM (SKN-1)[1]
Chemical Information
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No. CAS 1158607-44-3
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Peso molecular 430.80
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Fòrmula C21H26Cl3NO2
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SMILES
CCOC1=C(C(Cl)=CC(CNC2CCCC2)=C1)OCC3=CC=C(C=C3)Cl.[H]Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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J Hazard Mater
Isobavachalcone confers protection against Cryptococcus neoformans-induced ferroptosis in Caenorhabditis elegans via lifespan extension and GSH-GPX-1 axis modulation. [Abstract]2025 Mar 18:492:137969. PMID: 40154123
Pureza y Documentación
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Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ML358 Related Classifications
HY-123693 Related Classifications
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