Phyllalbine
Phyllalbine is an alkaloid compound found in the roots of Convolvulus subhirsutus, exhibiting both central and peripheral sympathomimetic effects, making it a promising candidate for neurological disease research.
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- No. CAS: 4540-25-4
- Fòrmula: C16H21NO4
- Peso molecular:291.34
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 4540-25-4
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Peso molecular 291.34
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Fòrmula C16H21NO4
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SMILES
O=C(C(C=C1)=CC(OC)=C1O)O[C@H](C[C@]2([H])CC3)C[C@]3([H])N2C
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Research Protocol for Neurological Diseases
PINK1/Parkin-mediated mitophagy pathway is a mitochondrial quality-control signaling axis in which mitochondrial depolarization stabilizes PINK1 on damaged mitochondria, activates Parkin recruitment and E3 ubiquitin ligase activity, promotes ubiquitination of outer mitochondrial membrane proteins, recruits selective autophagy adaptors, and drives lysosomal degradation of damaged mitochondria. In neurological disease research, this pathway is experimentally important because neurons, especially dopaminergic neurons, are highly dependent on mitochondrial integrity, and defective mitochondrial turnover can lead to mitochondrial dysfunction, oxidative stress, impaired neuronal survival, α-synuclein accumulation, and neuroinflammatory damage-associated signals. The genetic disease link is strongest in Parkinson’s disease because mutations in PRKN/parkin cause autosomal recessive juvenile parkinsonism, mutations in PINK1 cause hereditary early-onset Parkinson’s disease, and Drosophila studie
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Phyllalbine Related Classifications
HY-N15338 Related Classifications
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