PRMT4-IN-3
PRMT4-IN-3 (compound 56) is a potent inhibitor of class I protein arginine methyltransferase (PRMT), targeting PRMT4 (IC50: 37 nM) and PRMT4 (IC50: 253 nM).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C23H29N7O
- Peso molecular:419.52
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas Histone Methyltransferase
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Actividad biológica
Descripciòn
IC50 & Target
IC50: 37 nM (PRMT4), 253 nM (PRMT6)[1]
Chemical Information
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Peso molecular 419.52
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Fòrmula C23H29N7O
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SMILES
O=C(N[C@H]1CN(CCNC)CC1)C2=CC3=NC=NC(NC4=CC=C(CN)C=C4)=C3C=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)