country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Referencia número: HY-P99818

Copy Link Print Information

Ramatercept

Name: Ramatercept
Brand: MedChemExpress
SKU: HY-P99818
Price: 400.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: ACE-031)

Revisión del cliente

Based on 1 Customer Validation

Ramatercept (ACE-031) is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy.

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: ≥99.0%
No. CAS: 1169766-01-1
Peso molecular:77.24 kDa

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ramatercept Chemical Structure

No. CAS: 1169766-01-1

Tamaño

Precio

Stock

Cantidad

Amount: USD 0.00

* Seleccione Cantidad antes de agregar artículos.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vivo
- Ensayo clínico
- Conjugated
- Reconsititution
- Format
- Aplicación
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

IC₅₀ & Target

soluble activin receptor 2, ACVR2^[2]

Ver todos los productos específicos de isoformas TGF-β Receptor :

In Vivo

Ramatercept (ACE-031) (10 mg/kg; s.c.; three times a week for 5 weeks) significantly increases the muscle mass of mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ensayo clínico

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

[ACVR2B (activin A receptor type 2B, ActR-IIB, ActRIIB)]2-IGHG1 Fc (Fragment constant)

Aplicación

ELISA, FACS, Functional assay

Chemical Information

No. CAS 1169766-01-1
Appearance Liquid
Peso molecular 77.24 kDa
Color Colorless to light yellow
SMILES

[Ramatercept]
Synonyms

ACE-031
Envío

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (256 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Inhibitory Antibodies User Guide (603 KB)

Referencias

[1]. Fariello R G, et al. A novel Biological (FOX-115) improves endurance of motor performances in old mice (P2. 4-033)[J]. 2019.

[2]. Feike Y, et al. Advances in research on pharmacotherapy of sarcopenia. Aging Med (Milton). 2021 Aug 9;4(3):221-233. [Content Brief]

[3]. Louvel É. Dopage: nouveaux médicaments influant sur la biogenèse musculaire et mitochondriale[J]. 2019.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtener un presupuesto En stock

Other size

Obtener un presupuesto

Amount: USD 0.00

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vivo
- Ensayo clínico
- Conjugated
- Reconsititution
- Format
- Aplicación
Chemical Information
Pureza y Documentación
Referencias

Nombre del producto:
Referencia número:
Cantidad:
MCE Japan Authorized Agent:

Nombre del producto:
No. CAS:
Species:
Pureza:
Cantidad:

Ramatercept

Protein A Agarose

Bradford Protein Assay Kit

Cell-ATP Viability Detection Kit

HOLO Human Interleukin-2 (IL-2) Detection Kit

PBS Buffer (1×)

Cytotoxicity LDH Assay Kit

DPBS Buffer (1×)

Ver todos los productos específicos de isoformas TGF-β Receptor