Spinorphin
Spinorphin is an inhibitor of enkephalin-degrading enzymes. Spinorphin inhibits aminopeptidase, dipeptidyl aminopeptidase III, angiotensin-converting enzyme and enkephalinase. Spinorphin possesses an antinociceptive effect.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 137201-62-8
- Fòrmula: C45H64N8O10
- Peso molecular:877.04
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Oocyte | IC50 |
48.1 pM
Compound: 5, spinorphin
|
Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current in presence of 20 nM LVVYPWA peptide by two electrode voltage clamping technique
Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current in presence of 20 nM LVVYPWA peptide by two electrode voltage clamping technique
|
[PMID: 17676725] |
| Oocyte | IC50 |
8.3 pM
Compound: 5, spinorphin
|
Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage clamping technique
Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage clamping technique
|
[PMID: 17676725] |
Chemical Information
-
No. CAS 137201-62-8
-
Peso molecular 877.04
-
Fòrmula C45H64N8O10
-
SMILES
C[C@@H](O)[C@@H](C(O)=O)NC([C@H](CC1=CNC2=CC=CC=C12)NC([C@H]3N(C([C@H](CC4=CC=C(C=C4)O)NC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H](CC(C)C)N)=O)=O)=O)=O)CCC3)=O)=O
-
Synonyms
LVV-hemorphin-4
-
Sequence
Leu-Val-Val-Tyr-Pro-Trp-Thr
-
Sequence Shortening
LVVYPWT
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Spinorphin Related Classifications
HY-P1044 Related Classifications
Powered by Bioz