Tetrapeptide-4
Based on 1 Customer Validation
Tetrapeptide-4 is a synthetic tetrapeptide. Tetrapeptide-4 upregulates hyaluronic acid synthetase, and collagen production in human dermal fibroblasts. Tetrapeptide-4 reduces skin aging, improves skin firmness, elasticity, and appearance, and benefits hair.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.54%
- No. CAS: 960608-16-6
- Fòrmula: C14H22N4O7
- Peso molecular:358.35
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Almacenamiento:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
Collagen I |
Collagen II |
In Vitro
Tetrapeptide-4 (compound GEPG) (1 μg/mL; 24 h) upregulates FN1, HAS1, COL1A1, and COL1A2 mRNA expression in human dermal fibroblasts[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human dermal fibroblasts (HDFs) derived from neonatal foreskin
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Concentration:1 μg/mL
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Incubation Time:24 h
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Result:Increased fibronectin 1 (FN1) mRNA expression to a normalized level of 17 relative to control.
Increased hyaluronic acid synthetase 1 (HAS1) mRNA expression.
Increased collagen I alpha-1 chain (COL1A1) mRNA expression.
Increased collagen I alpha-2 chain (COL1A2) mRNA expression.
Chemical Information
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No. CAS 960608-16-6
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Appearance Solid
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Peso molecular 358.35
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Fòrmula C14H22N4O7
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Color White to off-white
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Sequence
Gly-Glu-Pro-Gly
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Sequence Shortening
GEPG
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
In Vitro:
DMSO : 33.33 mg/mL (93.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7906 mL | 13.9528 mL | 27.9057 mL | 69.7642 mL |
| 5 mM | 0.5581 mL | 2.7906 mL | 5.5811 mL | 13.9528 mL | |
| 10 mM | 0.2791 mL | 1.3953 mL | 2.7906 mL | 6.9764 mL | |
| 15 mM | 0.1860 mL | 0.9302 mL | 1.8604 mL | 4.6509 mL | |
| 20 mM | 0.1395 mL | 0.6976 mL | 1.3953 mL | 3.4882 mL | |
| 25 mM | 0.1116 mL | 0.5581 mL | 1.1162 mL | 2.7906 mL | |
| 30 mM | 0.0930 mL | 0.4651 mL | 0.9302 mL | 2.3255 mL | |
| 40 mM | 0.0698 mL | 0.3488 mL | 0.6976 mL | 1.7441 mL | |
| 50 mM | 0.0558 mL | 0.2791 mL | 0.5581 mL | 1.3953 mL | |
| 60 mM | 0.0465 mL | 0.2325 mL | 0.4651 mL | 1.1627 mL | |
| 80 mM | 0.0349 mL | 0.1744 mL | 0.3488 mL | 0.8721 mL |
Tetrapeptide-4 Related Classifications
HY-P5237 Related Classifications
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