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United States

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Referencia número: HY-149069

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TSC25

TSC25 is a potent cruzipain (CZP) inhibitor, with an IC₅₀ of 3.34 nM and a pIC₅₀ of 8.48.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₁₄H₁₈Cl₂N₄OS
Peso molecular:361.29

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

TSC25 Chemical Structure

Tamaño

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

TSC25 is a potent cruzipain (CZP) inhibitor, with an IC₅₀ of 3.34 nM and a pIC₅₀ of 8.48^[1].

Ver todos los productos específicos de isoformas Cathepsin :

Chemical Information

Peso molecular 361.29
Fòrmula C₁₄H₁₈Cl₂N₄OS
SMILES

NC(N/N=C(C1=CC=C(C(Cl)=C1)Cl)\CCN2CCOCC2)=S
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Jasinski G, et al. Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors. Eur J Med Chem. 2023 Apr 7;254:115345. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Actividad biológica
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Chemical Information
Pureza y Documentación
Referencias

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TSC25

Ver todos los productos específicos de isoformas Cathepsin

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

TSC25 Related Classifications

HY-149069 Related Classifications

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Keywords

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