VH4127
VH4127 is a cyclic peptide targeting the low density lipoprotein receptor (LDLR) with a KD of 18 nM for hLDLR. VH4127, bearing non-natural amino acid residues, specifically binds to rodent and human epidermal growth factor (EGF) homology domain of LDLR.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C40H71N15O9S4
- Peso molecular:1034.35
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
|
hLDLR 18 nM (Kd) |
Chemical Information
-
Peso molecular 1034.35
-
Fòrmula C40H71N15O9S4
-
Sequence
Pr-cyclo[{d-Cys}-Met-Thz-Arg-Leu-Arg-Gly-Pen]-NH2
-
Sequence Shortening
Pr-cyclo[{d-Cys}-M-Thz-RLRG-Pen]-NH2
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Xue Yang, et al. Preparation and In Vitro Validation of a Cucurbit[7]uril-Peptide Conjugate Targeting the LDL Receptor. J Med Chem. 2023 Jul 13;66(13):8844-8857. [Content Brief]
[2]. Angélina Acier, et al. LDL receptor-peptide conjugate as in vivo tool for specific targeting of pancreatic ductal adenocarcinoma. Commun Biol. 2021 Aug 19;4(1):987. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VH4127 Related Classifications
HY-P10697 Related Classifications
Powered by Bioz