ZC9
ZC9 is a androgen receptor (AR) molecular glue degrader. ZC9 directly binds to AR and inhibits Dihydrotestosterone-induced nuclear translocation of AR. ZC9 promotes AR degradation via the ubiquitin-proteasome system and suppresses AR transcriptional activity. ZC9 significantly decreases the mRNA levels of other AR downstream genes, including PSA, TMPRSS2, and PMEPA1. ZC9 promotes Apoptosis. ZC9 exhibits anticancer activity against prostate cancer.
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- No. CAS: 2757513-79-2
- Fòrmula: C24H19N3O3S2
- Peso molecular:461.56
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 2757513-79-2
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Peso molecular 461.56
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Fòrmula C24H19N3O3S2
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SMILES
O=C(C1=CC=C(C=C(OCC2=C(C)ON=C2C)C=C3)C3=C1)NC4=NC(C5=CC=CS5)=CS4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZC9 Related Classifications
HY-179123 Related Classifications
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