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CSF1R - colony stimulating factor 1 receptor Gene

Species: Sus scrofa

Gene Type: protein coding

Gene ID: 100517086

About CSF1R

Primary_assembly 2: 151,102,147-151,147,633 reverse strand.Sscrofa11.1:CM000813.5

This gene has 2 transcripts (splice variants), 273 orthologues and 52 paralogues. Broad expression in spleen (RPKM 259.), lung (RPKM 124.2) and 5 other tissues.

CSF1R Products (3)

mRNA	Protein	Name
XM_003124100.6	XP_003124148.5	macrophage colony-stimulating factor 1 receptor isoform X1
XM_013995332.2	XP_013850786.2	macrophage colony-stimulating factor 1 receptor isoform X3
XM_021085015.1	XP_020940674.1	macrophage colony-stimulating factor 1 receptor isoform X2

CSF1R Protein Structure

IG_like

PKc_like

0
200
400
600
800
1000
1053 a.a.

Protein Preferred Names	Protein Names
macrophage colony-stimulating factor 1 receptor

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-16749	Pexidartinib		99.64%	Yes
HY-16749A	Pexidartinib hydrochloride		99.82%	Yes
HY-12297	Sulfatinib	Inhibitor	99.52%	Unkown

Clinical Phase

Bioactive Molecules (18)

Cat. No.	Product Name	Effect	Purity	Phase
HY-50905	Dovitinib	Inhibitor	99.88%	Phase 3
HY-153920	Pimicotinib	Inhibitor	99.92%	Phase 3
HY-145601	Tinengotinib	Inhibitor	99.57%	Phase 3
HY-124526	Chiauranib	Inhibitor	98.97%	Phase 3
HY-12768A	Sotuletinib hydrochloride	Inhibitor	99.43%	Phase 2
HY-109190	Seralutinib	Inhibitor	99.94%	Phase 2
HY-109086	Edicotinib	Inhibitor	99.68%	Phase 2
HY-19772	GSK3117391	Inhibitor	99.40%	Phase 2
HY-136362	ARRY-382	Inhibitor	99.95%	Phase 2
HY-152830A	Adrixetinib TFA		99.82%	Phase 2
HY-12768B	Sotuletinib dihydrochloride	Inhibitor	/	Phase 2
HY-109086A	Edicotinib hydrochloride	Inhibitor	/	Phase 2
HY-114153	PLX5622	Inhibitor	99.95%	Phase 1
HY-114153A	PLX5622 hemifumarate	Inhibitor	99.93%	Phase 1
HY-100491	H3B-6527	Inhibitor	98.0%	Phase 1
HY-111787	Elzovantinib	Inhibitor	99.93%	Phase 1
HY-101768	PRN1371	Inhibitor	99.78%	Phase 1
HY-10204	OSI-930		98.33%	Phase 1

Bioactive MoleculesInhibitory Antibodies (6)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99245	Emactuzumab	Inhibitor	97.60%	Phase 3
HY-P990043	Iluzanebart		98.63%	Phase 2
HY-P99452	Axatilimab	Inhibitor	99.59%	Phase 2
HY-P99259	Cabiralizumab	Inhibitor	99.73%	Phase 2
HY-P99368	Lacnotuzumab	Inhibitor	99.9%	Phase 2
HY-P991048	AMG-820	Inhibitor	98%	Phase 2

Pre-clinical Phase

Bioactive Molecules (61)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-114153C	PLX5622 in AIN-76A Diet (1200 ppm)	Inhibitor	/	Unkown
HY-12768	Sotuletinib	Inhibitor	99.97%	Unkown
HY-132166	Velzatinib	Inhibitor	99.40%	Unkown
HY-10408	Ki20227	Inhibitor	99.51%	Unkown
HY-159838	Enrupatinib	Inhibitor	98.90%	Unkown
HY-161025	SYHA1813	Inhibitor	99.46%	Unkown
HY-101774	CSF1R-IN-1	Inhibitor	98.04%	Unkown
HY-159108	AZ683	Inhibitor	98.57%	Unkown
HY-117244	AZD7507	Inhibitor	99.57%	Unkown
HY-147615	CSF1R-IN-12		98.75%	Unkown
HY-122906	JTE-952	Inhibitor	99.86%	Unkown
HY-152830	Adrixetinib		99.55%	Unkown
HY-126297	c-Fms-IN-10	Inhibitor	98.63%	Unkown
HY-139990	CSF1R-IN-3	Inhibitor	98.10%	Unkown
HY-112451	cFMS Receptor Inhibitor II	Inhibitor	99.88%	Unkown
HY-132935	BPR1R024	Inhibitor	98.50%	Unkown
HY-160842	CSF1R-IN-24	Inhibitor	98.10%	Unkown
HY-117273	AZ304	Inhibitor	99.77%	Unkown
HY-119942	c-Fms-IN-8	Inhibitor	99.50%	Unkown
HY-101526	GENZ-882706	Inhibitor	/	Unkown
HY-13075	c-Fms-IN-3	Inhibitor	99.69%	Unkown
HY-132935A	BPR1R024 mesylate	Inhibitor	/	Unkown
HY-RS03228	CSF1R Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-13493	AC710	Inhibitor	99.13%	Unkown
HY-13496	JNJ-28312141	Inhibitor	/	Unkown
HY-101034	CHMFL-ABL/KIT-155		/	Unkown
HY-174366	JMC14	Inhibitor	/	Unkown
HY-13496A	JNJ-28312141 hydrochloride	Inhibitor	/	Unkown
HY-144040	CSF1R-IN-4		/	Unkown
HY-144041	CSF1R-IN-5	Inhibitor	/	Unkown
HY-144042	CSF1R-IN-6		/	Unkown
HY-147608	CSF1R-IN-7	Inhibitor	/	Unkown
HY-147609	CSF1R-IN-8	Inhibitor	/	Unkown
HY-147610	CSF1R-IN-9	Inhibitor	/	Unkown
HY-147611	CSF1R-IN-10	Inhibitor	/	Unkown
HY-147616	CSF1R-IN-13		/	Unkown
HY-147617	CSF1R-IN-14		/	Unkown
HY-153012	Axl/Mer/CSF1R-IN-1	Inhibitor	/	Unkown
HY-153243	IACS-9439	Inhibitor	/	Unkown
HY-153277	Axl/Mer/CSF1R-IN-2	Inhibitor	/	Unkown
HY-153920A	Pimicotinib hydrochloride	Inhibitor	/	Unkown
HY-155001	CSF1R-IN-15	Inhibitor	/	Unkown
HY-155550	CSF1R-IN-17	Antagonist	/	Unkown
HY-157422	CSF1R-IN-19	Inhibitor	/	Unkown
HY-157996	CSF1R-IN-21	Inhibitor	/	Unkown
HY-158050	PXB17	Inhibitor	/	Unkown
HY-158148	CSF1R-IN-23	Inhibitor	/	Unkown
HY-158363	CSF1R-IN-25	Inhibitor	/	Unkown
HY-161084	CSF1R-IN-18	Inhibitor	/	Unkown
HY-162309	CSF1R-IN-20	Inhibitor	/	Unkown
HY-162415	CSF1R-IN-22		/	Unkown
HY-168954	CSF1R-IN-26		/	Unkown
HY-176194	Antifibrotic agent 1		/	Unkown
HY-183569	CSF1R-IN-27	Inhibitor	/	Unkown
HY-183931	NPA101.3	Inhibitor	/	Unkown
HY-RS03229	Csf1r Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS03230	Csf1r Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-13493A	AC710 Mesylate	Inhibitor	/	Unkown
HY-159503A	Segigratinib hydrochloride	Inhibitor	/	Unkown
HY-164529	SJ-C1044	Inhibitor	98.63%	Unkown
HY-174606	Human IL34 mRNA		/	Unkown

Bioactive MoleculesInhibitory Antibodies (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990125	Anti-Mouse CSF1R/CD115 Antibody (AFS98)		99.38%	Unkown
HY-P990849	Anti-CSF1R/CD115 Antibody (2-4A5-4)	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	CSF1R	NCBI	NCBI:1436