2 Results for "

10199

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "10199" in MCE Product Catalog:

5
Ibutamoren
Ibutamoren
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5 Cited Publications
Cat. No.: HY-10199A
CAS No.: 159634-47-6
Purity:  98.52%
Synonyms: MK-677 free base; MK-0677 free base
Target:  

GHSR Insulin Receptor

Research Areas:  

Neurological Disease Metabolic Disease

Ibutamoren (MK-677 free base; MK-0677 free base) is an orally active non-peptide growth hormone secretagogue receptor agonist. Ibutamoren activates signal cascades by mimicking endogenous ligands, triggers pulsatile release of growth hormone from the pituitary gland, and increases serum levels of IGF-1 and insulin-like growth factor-binding protein 3. Ibutamoren not only increases the frequency of growth hormone pulses in male individuals, but also promotes elevated bone formation markers in female individuals with postmenopausal osteoporosis. The combination of Ibutamoren with Alendronate sodium hydrate (HY-11101) significantly increases bone mineral density at the femoral neck. However, Ibutamoren may cause mild, reversible adverse reactions such as increased appetite, fluid retention, and elevated fasting blood glucose. Ibutamoren has been widely used in studies related to idiopathic growth hormone deficiency, sarcopenia, Alzheimer's disease, and osteoporosis .
PDE10A Human Pre-designed siRNA Set A
PDE10A Human Pre-designed siRNA Set A
Cat. No.: HY-RS10199
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

PDE10A Human Pre-designed siRNA Set A contains three designed siRNAs for PDE10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Assay Types