2. Gene
  3. IMP4 - IMP U3 small nucleolar ribonucleoprotein 4 Gene

IMP4 - IMP U3 small nucleolar ribonucleoprotein 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BXDC4

Gene ID: 92856 | Gene type: protein coding

About IMP4

Cytogenetic location: 2q21.1 Genomic coordinates (GRCh38): 2:130,342,897-130,347,967 (from NCBI)

This gene has 17 transcripts (splice variants), 200 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 11.8), appendix (RPKM 9.3) and 25 other tissues.

Summary

The protein encoded by this gene, along with IMP3 and MPP10, is part of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP) complex. This complex is necessary for the early cleavage steps of pre-18S ribosomal RNA processing. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

IMP4 Products(16)

mRNA Protein Name
NM_001320304.2 NP_001307233.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform b
NM_001320305.2 NP_001307234.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform c
NM_001320306.2 NP_001307235.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform d
NM_001320307.2 NP_001307236.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform d
NM_001320309.2 NP_001307238.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform e
NM_001320310.2 NP_001307239.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform e
NM_001320311.2 NP_001307240.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform f
NM_001371725.1 NP_001358654.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform g
NM_001371726.1 NP_001358655.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform h
NM_001371728.1 NP_001358657.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform i
NM_001371730.1 NP_001358659.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform j
NM_001371731.1 NP_001358660.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform e
NM_001371732.1 NP_001358661.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform e
NM_001371733.1 NP_001358662.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform e
NM_001371734.1 NP_001358663.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform e
NM_033416.3 NP_219484.1 U3 small nucleolar ribonucleoprotein protein IMP4 isoform a

IMP4 Protein Structure

Brix

Brix: Brix domain (87 - 258)

  • 0
  • 100
  • 200
  • 291 a.a.
Protein Preferred Names Protein Names

U3 small nucleolar ribonucleoprotein protein IMP4

IMP4 homolog, U3 small nucleolar ribonucleoprotein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12826 IMB-XH1 Inhibitor ≥98.0% Unkown
HY-RS06794 IMP4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus IMP4 MGD MGI:106572
Felis catus IMP4 VGNC VGNC:62917
Bos taurus IMP4 VGNC VGNC:30183
Rattus norvegicus IMP4 RGD RGD:1308463
Macaca mulatta IMP4 VGNC VGNC:73689
Others IMP4 NCBI