2. Gene
  3. LRRK2 - leucine rich repeat kinase 2 Gene

LRRK2 - leucine rich repeat kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca fascicularis
Gene ID: 102126106 | Gene type: protein coding

About LRRK2

Primary_assembly 11: 39,064,274-39,209,351 forward strand.Macaca_fascicularis_6.0:CM021949.1

This gene has 6 transcripts (splice variants), 191 orthologues and 22 paralogues.

LRRK2 Products(4)

mRNA Protein Name
XM_005570586.3 XP_005570643.2 leucine-rich repeat serine/threonine-protein kinase 2 isoform X3
XM_045365029.1 XP_045220964.1 leucine-rich repeat serine/threonine-protein kinase 2 isoform X4
XM_005570583.3 XP_005570640.2 leucine-rich repeat serine/threonine-protein kinase 2 isoform X2
XM_005570582.3 XP_005570639.2 leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
Protein Preferred Names Protein Names

leucine-rich repeat serine/threonine-protein kinase 2

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-112809 GSK2646264 Inhibitor 98.39% Phase 1
Pre-clinical Phase
Bioactive Molecules (61)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100411 MLi-2 Inhibitor 99.80% Unkown
HY-13687 IKK 16 Inhibitor 99.88% Unkown
HY-10875 LRRK2-IN-1 Inhibitor 99.04% Unkown
HY-148030 XL01126 Inhibitor 98.90% Unkown
HY-12477 PF-06447475 Inhibitor 99.94% Unkown
HY-40294 Indazole Inhibitor 99.83% Unkown
HY-15796 GNE0877 Inhibitor 99.81% Unkown
HY-13237 GSK2578215A Inhibitor 99.82% Unkown
HY-18163 GNE-7915 Inhibitor 99.82% Unkown
HY-13687A IKK 16 hydrochloride Inhibitor 99.95% Unkown
HY-13488 HG-10-102-01 Inhibitor 99.55% Unkown
HY-120085 PFE-360 Inhibitor 99.10% Unkown
HY-P5979 LRRKtide Substrate 99.94% Unkown
HY-12282 GNE-9605 Inhibitor 99.51% Unkown
HY-15800A CZC-25146 Inhibitor 99.10% Unkown
HY-155150 JH-XII-03-02 Inhibitor 99.41% Unkown
HY-111493 LRRK2 inhibitor 1 Inhibitor 99.80% Unkown
HY-152107 LRRK2-IN-7 Inhibitor 98.03% Unkown
HY-156429 MK-1468 Inhibitor 99.69% Unkown
HY-B0792 CZC-54252 Inhibitor 98.05% Unkown
HY-142647 EB-42486 Inhibitor 99.62% Unkown
HY-163064 CC-3240 Degrader 98.23% Unkown
HY-16936 JH-II-127 Inhibitor 98.0% Unkown
HY-18163A GNE-7915 tosylate Inhibitor 99.06% Unkown
HY-112855 PF-06454589 Inhibitor 99.91% Unkown
HY-W107722 IN04 98.51% Unkown
HY-148353 PF-06455943 Inhibitor 98.21% Unkown
HY-75368 SRI-31255 Inhibitor 99.88% Unkown
HY-152107A (R,R)-LRRK2-IN-7 Inhibitor / Unkown
HY-145317 LRRK2-IN-2 Inhibitor / Unkown
HY-145318 LRRK2-IN-3 Inhibitor / Unkown
HY-175651 LRRK2-IN-20 Inhibitor / Unkown
HY-156167 LRRK2-IN-10 Inhibitor / Unkown
HY-162699 LY2023-001 Inhibitor / Unkown
HY-153058 LRRK2-IN-8 Inhibitor / Unkown
HY-174420 RN277 Inhibitor / Unkown
HY-171802 PROTAC LRRK2 Degrader-2 Degrader / Unkown
HY-158365 LRRK2-IN-14 Inhibitor / Unkown
HY-177016 LRRK2-IN-19 Inhibitor / Unkown
HY-168041 LRRK2-IN-15 Inhibitor / Unkown
HY-151444 LRRK2-IN-6 Inhibitor / Unkown
HY-172952 LRRK2-IN-17 Inhibitor / Unkown
HY-178796 PROTAC LRRK2 Degrader-4 Degrader / Unkown
HY-182928 LRRK2-IN-21 Inhibitor / Unkown
HY-171801 PROTAC LRRK2 Degrader-1 Degrader / Unkown
HY-151441 LRRK2-IN-5 Inhibitor / Unkown
HY-178797 PROTAC LRRK2 Degrader-3 Degrader / Unkown
HY-161571 LRRK2-IN-13 Inhibitor / Unkown
HY-186110 PROTAC LRRK2 Degrader-5 Degrader / Unkown
HY-134562 PF-06371900 Inhibitor 99.43% Unkown
HY-180320 Lu AF58786 Inhibitor / Unkown
HY-165543 SRI-29132 Inhibitor / Unkown
HY-169576 LRRK2-IN-16 Inhibitor / Unkown
HY-174427 RN341 Inhibitor / Unkown
HY-144074 LRRK2-IN-4 Inhibitor / Unkown
HY-161570 LRRK2-IN-12 Inhibitor / Unkown
HY-B0792A CZC-54252 hydrochloride Inhibitor 98.44% Unkown
HY-153103 LRRK2/NUAK1/TYK2-IN-1 Inhibitor / Unkown
HY-P10636 Nictide / Unkown
HY-15800 CZC-25146 hydrochloride Inhibitor / Unkown
HY-181046 Multi-kinase-IN-14 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens LRRK2 NCBI NCBI:120892