2. PROTAC Autophagy
  3. PROTACs LRRK2
  4. PROTAC LRRK2 Degrader-3

PROTAC LRRK2 Degrader-3 (compound 6) is a PROTAC LRRK2 degrader with a DC50 of 0.17 nM. PROTAC LRRK2 Degrader-3 can be used for research in Parkinson’s disease and inflammation.
(Pink: LRRK2 ligand (HY-177016); Blue: Cereblon ligand (HY-163927); Black: linker (HY-178830)).

For research use only. We do not sell to patients.

PROTAC LRRK2 Degrader-3

PROTAC LRRK2 Degrader-3 Chemical Structure

CAS No. : 3080678-98-1

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PROTAC LRRK2 Degrader-3 Related Antibodies

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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Description

PROTAC LRRK2 Degrader-3 (compound 6) is a PROTAC LRRK2 degrader with a DC50 of 0.17 nM. PROTAC LRRK2 Degrader-3 can be used for research in Parkinson’s disease and inflammation[1]. (Pink: LRRK2 ligand (HY-177016); Blue: Cereblon ligand (HY-163927); Black: linker (HY-178830)).

IC50 & Target[1]

LRRK2

0.17 nM (DC50)

Molecular Weight

802.96

Formula

C44H54N10O5
CAS No.
SMILES

CC1(CC1)OC2=CC=C3C(C(C4=NC=NC(N5CCN(C[C@H]6CC[C@H](OC7CCN(C8=CC(N(C)C(N9C%10C(NC(CC%10)=O)=O)=O)=C9C=C8)CC7)CC6)CC5)=C4)=NN3)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC LRRK2 Degrader-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC LRRK2 Degrader-33080678-98-1PROTACsLRRK2Leucine-rich repeat kinase 2Parkinson’s DiseaseinflammationInhibitorinhibitorinhibit

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