2. Autophagy
  3. LRRK2
  4. MK-1468

MK-1468 is a high selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 0.8 nM. MK-1468 can be used in study Parkinson’s disease.

For research use only. We do not sell to patients.

MK-1468 Chemical Structure

MK-1468 Chemical Structure

CAS No. : 2769107-89-1

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MK-1468 Related Antibodies

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Description

MK-1468 is a high selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 0.8 nM. MK-1468 can be used in study Parkinson’s disease[1].

Molecular Weight

501.02

Formula

C26H33ClN4O4
CAS No.
SMILES

ClC(C(N1CCN([C@]2([C@H](COC2)O)C)CC1)=C3)=CC(C=N4)=C3C=C4NC([C@@H]5C6(CCOCC6)C5)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MK-1468 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MK-14682769107-89-1MK1468MK 1468LRRK2Leucine-rich repeat kinase 2LRRK2 InhibitorBrain-PenetrantParkinson’s DiseaseInhibitorinhibitorinhibit

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