2. Gene
  3. CLEC10A - C-type lectin domain containing 10A Gene

CLEC10A - C-type lectin domain containing 10A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as HML; MGL; HML2; CD301; CLECSF13; CLECSF14

Gene ID: 10462 | Gene type: protein coding

About CLEC10A

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,074,537-7,080,251 (from NCBI)

This gene has 6 transcripts (splice variants), 148 orthologues and 14 paralogues. Broad expression in appendix (RPKM 13.9), small intestine (RPKM 10.3) and 21 other tissues.

Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

CLEC10A Products(3)

mRNA Protein Name
NM_001330070.2 NP_001316999.1 C-type lectin domain family 10 member A isoform 3
NM_006344.4 NP_006335.2 C-type lectin domain family 10 member A isoform 2
NM_182906.4 NP_878910.1 C-type lectin domain family 10 member A isoform 1

CLEC10A Protein Structure

Lectin_N

Lectin_N: Hepatic lectin, N-terminal domain (7 - 128)

Lectin_C

Lectin_C: Lectin C-type domain (199 - 305)

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  • 316 a.a.
Protein Preferred Names Protein Names

C-type lectin domain family 10 member A

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived)

Recombinant CLEC10A Proteins

Cat. No. Product Name Accession Purity
HY-P72689 CLEC10A/CD301 Protein, Human (HEK293, His) Q8IUN9 (Q61-H316) ≥95%
HY-P75676 CLEC10A/CD301 Protein, Human (HEK293, Fc) Q8IUN9-2 (Q61-H292) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02779 CLEC10A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CLEC10A VGNC VGNC:55799
Rattus norvegicus CLEC10A RGD RGD:621158
Macaca mulatta CLEC10A VGNC VGNC:71188
Mus musculus CLEC10A NCBI
Others CLEC10A NCBI