DPYSL4 - dihydropyrimidinase like 4 Gene

Also Known as CRMP3; DRP-4; ULIP4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10570

About DPYSL4

Cytogenetic location: 10q26.3 Genomic coordinates (GRCh38): 10:132,186,948-132,205,759 (from NCBI)

This gene has 5 transcripts (splice variants), 201 orthologues and 5 paralogues. Biased expression in brain (RPKM 6.6), heart (RPKM 2.6) and 6 other tissues.

Summary

Enables filamin binding activity. Predicted to be involved in nervous system development. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

DPYSL4 Products (1)

mRNA Protein Name
NM_006426.3 NP_006417.2 dihydropyrimidinase-related protein 4

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables filamin binding IPI
IPI: Inferred from physical interaction
25358863 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
21900206 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DPYSL4 Protein Structure

Amidohydro_1

Amidohydro_1: Amidohydrolase family (64 - 413)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 572 a.a.
Protein Preferred Names Protein Names

dihydropyrimidinase-related protein 4

  • CRMP-3

DPYSL4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
DPYSL4 O14531 KIF1B Homo sapiens O60333-2
Y2H Array
32814053
Intra
DPYSL4 O14531 KIF1B Homo sapiens O60333-2
Validated Y2H
32814053
Intra
DPYSL4 O14531 KIF1B Homo sapiens O60333-2
Y2H Pooling
32814053
Intra
DPYSL4 O14531 DPYSL2 Homo sapiens Q16555
Anti Tag CoIP
33961781
Intra
DPYSL4 O14531 DPYSL2 Homo sapiens Q16555
Y2H
21900206
Intra
DPYSL4 O14531 TRIP13 Homo sapiens Q15645
Y2H Prey Pooling
25416956
Intra
DPYSL4 O14531 TRIP13 Homo sapiens Q15645
Validated Y2H
25416956
Intra
DPYSL4 O14531 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra
DPYSL4 O14531 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra
DPYSL4 O14531 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra
DPYSL4 O14531 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Intra
DPYSL4 O14531 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra
DPYSL4 O14531 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra
DPYSL4 O14531 RBPMS Homo sapiens Q93062
Y2H Prey Pooling
25416956
Intra
DPYSL4 O14531 RBPMS Homo sapiens Q93062
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

DPYSL4 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82818 CRMP3 Antibody (YA2563) WB Rat
HY-P82818A CRMP3 Antibody (YA2563)(PBS only) WB Rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03983 DPYSL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus DPYSL4 VGNC VGNC:61617
Rattus norvegicus DPYSL4 RGD RGD:2409
Bos taurus DPYSL4 VGNC VGNC:28197
Macaca mulatta DPYSL4 VGNC VGNC:71986
Canis familiaris DPYSL4 VGNC VGNC:49877
Mus musculus DPYSL4 MGD MGI:1349764
Others DPYSL4 NCBI