Stk38 - serine/threonine kinase 38 Gene

Also Known as Ndr1; 5830476G13Rik; 9530097A09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 106504

Summary

Predicted to enable several functions, including ATP binding activity; magnesium ion binding activity; and mitogen-activated protein kinase kinase kinase binding activity. Predicted to be involved in intracellular signal transduction; negative regulation of MAP kinase activity; and peptidyl-serine phosphorylation. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytosol and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and nose. Orthologous to human STK38 (serine/threonine kinase 38). [provided by Alliance of Genome Resources, Apr 2022]

Stk38 Products (2)

mRNA Protein Name
NM_001357173.1 NP_001344102.1 serine/threonine-protein kinase 38
NM_134115.3 NP_598876.1 serine/threonine-protein kinase 38

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21730291 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase 38

  • NDR1 protein kinase

  • nuclear Dbf2-related kinase 1

Stk38 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Stk38 Q91VJ4 STK4 Homo sapiens Q13043
Anti Tag CoIP
21730291
Intra
Stk38 Q91VJ4 Mical1 Mus musculus Q8VDP3
Anti Tag CoIP
21730291
Intra
Stk38 Q91VJ4 Mical1 Mus musculus Q8VDP3
Anti Bait CoIP
21730291
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-10211 Tanespimycin 99.01% Phase 3

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13939 STK38L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-10211S Tanespimycin-d5 / Unkown
HY-RS13938 STK38 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18409 Stk38 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24890 Stk38 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stk38 NCBI NCBI:11329