2. Gene
  3. ARPP19 - cAMP regulated phosphoprotein 19 Gene

ARPP19 - cAMP regulated phosphoprotein 19 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ENSAL; ARPP16; ARPP-16; ARPP-19

Gene ID: 10776 | Gene type: protein coding

About ARPP19

Cytogenetic location: 15q21.2 Genomic coordinates (GRCh38): 15:52,547,045-52,569,446 (from NCBI)

This gene has 13 transcripts (splice variants), 193 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 79.8), thyroid (RPKM 29.3) and 24 other tissues.

Summary

The 19-kD cAMP-regulated phosphoprotein plays a role in regulating mitosis by inhibiting protein phosphatase-2A (PP2A; see MIM 176915) (summary by Gharbi-Ayachi et al., 2010 [PubMed 21164014]).[supplied by OMIM, Feb 2011]

ARPP19 Products(5)

mRNA Protein Name
NM_001306191.2 NP_001293120.1 cAMP-regulated phosphoprotein 19 isoform 1
NM_001306195.1 NP_001293124.1 cAMP-regulated phosphoprotein 19 isoform 2
NM_001306196.2 NP_001293125.1 cAMP-regulated phosphoprotein 19 isoform 1
NM_001330309.2 NP_001317238.1 cAMP-regulated phosphoprotein 19 isoform 3
NM_006628.6 NP_006619.1 cAMP-regulated phosphoprotein 19 isoform 2

ARPP19 Protein Structure

Endosulfine

Endosulfine: cAMP-regulated phosphoprotein/endosulfine conserved region (22 - 79)

  • 0
  • 100
  • 112 a.a.
Protein Preferred Names Protein Names

cAMP-regulated phosphoprotein 19

cAMP-regulated phosphoprotein 19kDa

Related Diseases

Diseases Alias
Mega-Corpus-Callosum Syndrome With Cerebellar Hypoplasia And Cortical Malformations

MCCCHCM
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01025 ARPP19 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ARPP19 VGNC VGNC:38133
Felis catus ARPP19 VGNC VGNC:104359
Bos taurus ARPP19 VGNC VGNC:26167
Mus musculus ARPP19 MGD MGI:1891691
Rattus norvegicus ARPP19 RGD RGD:71054