CCNI - cyclin I Gene

Homo sapiens

Also known as CYI; CYC1; CCNI1

Gene ID: 10983 | Gene type: protein coding

About CCNI

Cytogenetic location: 4q21.1 Genomic coordinates (GRCh38): 4:77,047,155-77,075,989 (from NCBI)

This gene has 9 transcripts (splice variants), 239 orthologues and 18 paralogues. Ubiquitous expression in thyroid (RPKM 185.4), ovary (RPKM 178.6) and 25 other tissues.

Summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. [provided by RefSeq, Jan 2017]

CCNI Products(10)

mRNA	Protein	Name
NM_001348132.2	NP_001335061.1	cyclin-I isoform a
NM_001348133.2	NP_001335062.1	cyclin-I isoform a
NM_001348134.2	NP_001335063.1	cyclin-I isoform b
NM_001348135.2	NP_001335064.1	cyclin-I isoform c
NM_001348136.2	NP_001335065.1	cyclin-I isoform d
NM_001348137.2	NP_001335066.1	cyclin-I isoform e
NM_001348138.2	NP_001335067.1	cyclin-I isoform f
NM_001348139.2	NP_001335068.1	cyclin-I isoform g
NM_001348140.2	NP_001335069.1	cyclin-I isoform h
NM_006835.3	NP_006826.1	cyclin-I isoform a

CCNI Protein Structure

Cyclin_N

0
100
200
300
377 a.a.

Protein Preferred Names

Protein Names

cyclin-I

cyclin ITI

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02133	CCNI Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CCNI	RGD	RGD:1309209
Mus musculus	CCNI	MGD	MGI:1341077
Canis familiaris	CCNI	VGNC	VGNC:57402
Bos taurus	CCNI	VGNC	VGNC:26971
Felis catus	CCNI	VGNC	VGNC:60562
Macaca mulatta	CCNI	VGNC	VGNC:70733