Taar1 - trace amine-associated receptor 1 Gene

Also Known as Tar1; Trar1; taR-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 111174

Summary

Enables trace-amine receptor activity. Acts upstream of or within G protein-coupled receptor signaling pathway. Predicted to be integral component of membrane. Used to study schizophrenia. Orthologous to human TAAR1 (trace amine associated receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Taar1 Products (1)

mRNA Protein Name
NM_053205.1 NP_444435.1 trace amine-associated receptor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled amine receptor activity IDA
IDA: Inferred from direct assay
15718104 MGI
enables trace-amine receptor activity IDA
IDA: Inferred from direct assay
15718104 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
15718104 MGI
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
37935376 MGI
involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
37935376 MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
37935376 MGI
Cellular Component GO Annotation Evidence References Source
is active in plasma membrane IDA
IDA: Inferred from direct assay
37225986 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

trace amine-associated receptor 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-136109 Ulotaront hydrochloride Agonist 99.89% Phase 3
HY-136109A Ulotaront Agonist / Phase 3
HY-109157 Ralmitaront Agonist 99.92% Phase 2

Pre-clinical Phase

Bioactive Molecules (33)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-110098 Ro 5212773 99.85% Unkown
HY-103638 3-Methoxytyramine hydrochloride 98.23% Unkown
HY-12700 RO5256390 Agonist 98.75% Unkown
HY-108015 RO5263397 99.10% Unkown
HY-42346 ZH8651 Agonist 99.71% Unkown
HY-12699 RO5166017 Agonist 98.21% Unkown
HY-103638S 3-Methoxytyramine-d4 hydrochloride 98.66% Unkown
HY-103054 RO5203648 98.10% Unkown
HY-135065 3-Iodothyronamine hydrochloride Activator 99.5% Unkown
HY-W005394 2-Phenylpropan-1-amine hydrochloride 98.96% Unkown
HY-160001A ZH8659 hydrochloride Activator 99.21% Unkown
HY-176141 ZH8965 Agonist 99.48% Unkown
HY-117021 RO 5073012 Agonist / Unkown
HY-136109E SEP-363856 mesylate Agonist / Unkown
HY-157955 TAAR1 agonist 1 Agonist / Unkown
HY-157955A TAAR1 agonist 1 hydrochloride Agonist / Unkown
HY-160001 ZH8659 Activator / Unkown
HY-173451 TAAR1/5-H-2CR agonist-1 Agonist / Unkown
HY-173471 TRPA1 agonist-1 Agonist / Unkown
HY-183428 LK00764 Agonist / Unkown
HY-183489 TAAR1-agonist-4 Agonist / Unkown
HY-186230 RO5192022 Agonist / Unkown
HY-RS14130 TAAR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W502657 ZH8667 Agonist / Unkown
HY-W704807 3-Methoxytyramine-d3 hydrochloride / Unkown
HY-W755778 3-Iodothyronamine hydrochloride-13C6 / Unkown
HY-W909149 TAAR1 agonist 3 Agonist / Unkown
HY-W909173 TAAR1 agonist 2 Agonist / Unkown
HY-34713 N-Methylphenethylamine hydrochloride Agonist / Unkown
HY-RS16814 Taar1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23254 Taar1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W634602 (R)-RO5263397 Agonist / Unkown
HY-W680886 6-APDB / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Taar1 NCBI NCBI:134864