RO5192022
RO5192022 is a TAAR1 agonist and a radioligand for TAAR1 binding assays. RO5192022 exhibits antipsychotic-like properties. RO5192022 can be used in studies related to schizophrenia.
For research use only. We do not sell to patients.
- CAS No.: 1043489-40-2
- Formula: C9H8F2N2O
- Molecular Weight:198.17
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
TAAR1 |
TAAR1 is a trace amine-sensing GPCR enriched in the central nervous system. It regulates dopamine and serotonin monoamine neural circuits, and serves as a therapeutic target for schizophrenia, depression and drug addiction.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1043489-40-2
-
Molecular Weight 198.17
-
Formula C9H8F2N2O
-
SMILES
NC1=N[C@H](CO1)C2=CC=C(C=C2F)F
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Revel FG, et al.. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proceedings of the National Academy of Sciences of the United States of America. 2011 May 17;108(20):8485-90. [Content Brief]
[2]. Aleksandrov AA, et al.. The TAAR5 agonist α-NETA causes dyskinesia in mice. Neuroscience letters. 2019 Jun 21;704:208-211. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RO5192022 Related Classifications
HY-186230 Related Classifications
Powered by Bioz