C1QTNF6 - C1q and TNF related 6 Gene

Also Known as CTFP6; CTRP6; ZACRP6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 114904

About C1QTNF6

Cytogenetic location: 22q12.3 Genomic coordinates (GRCh38): 22:37,180,166-37,199,423 (from NCBI)

This gene has 7 transcripts (splice variants), 177 orthologues and 23 paralogues. Broad expression in endometrium (RPKM 12.1), placenta (RPKM 6.4) and 16 other tissues.

Summary

Predicted to enable identical protein binding activity. Predicted to be located in extracellular space. Predicted to be integral component of membrane. Predicted to be part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

C1QTNF6 Products (3)

mRNA Protein Name
NM_001365878.1 NP_001352807.1 complement C1q tumor necrosis factor-related protein 6 isoform 2 precursor
NM_031910.4 NP_114116.3 complement C1q tumor necrosis factor-related protein 6 isoform 1 precursor
NM_182486.2 NP_872292.1 complement C1q tumor necrosis factor-related protein 6 isoform 1 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32041782 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C1QTNF6 Protein Structure

Collagen

Collagen: Collagen triple helix repeat (20 copies) (97 - 138)

C1q

C1q: C1q domain (145 - 273)

  • 0
  • 100
  • 200
  • 278 a.a.
Protein Preferred Names Protein Names

complement C1q tumor necrosis factor-related protein 6

  • C1q and tumor necrosis factor related protein 6

C1QTNF6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
C1QTNF6 Q9BXI9 C1QTNF1 Homo sapiens Q9BXJ1-2
Y2H Array
32296183
Intra
C1QTNF6 Q9BXI9 C1QTNF1 Homo sapiens Q9BXJ1-2
Y2H Prey Pooling
32296183
Intra
C1QTNF6 Q9BXI9 C1QTNF1 Homo sapiens Q9BXJ1-2
Validated Y2H
32296183
Intra
C1QTNF6 Q9BXI9 SGTA Homo sapiens O43765
Validated Y2H
25416956
Intra
C1QTNF6 Q9BXI9 SGTA Homo sapiens O43765
Y2H Prey Pooling
32296183
Intra
C1QTNF6 Q9BXI9 SGTA Homo sapiens O43765
Y2H Array
32296183
Intra
C1QTNF6 Q9BXI9 SGTB Homo sapiens Q96EQ0
Y2H Array
32296183
Intra
C1QTNF6 Q9BXI9 SGTB Homo sapiens Q96EQ0
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Late-Onset Retinal Degeneration

  • LORD

  • Retinal Degeneration, Late-Onset, Autosomal Dominant

  • Autosomal Dominant Late-Onset Retinal Degeneration

  • Pigmentary Retinopathy

  • Retinal Degeneration, Late-Onset

  • Retinitis Pigmentosa
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01732 C1QTNF6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta C1QTNF6 VGNC VGNC:84562
Canis familiaris C1QTNF6 VGNC VGNC:38584
Felis catus C1QTNF6 VGNC VGNC:60224
Mus musculus C1QTNF6 MGD MGI:1919959
Rattus norvegicus C1QTNF6 RGD RGD:1307057
Bos taurus C1QTNF6 VGNC VGNC:26626
Others C1QTNF6 NCBI