Adm - adrenomedullin Gene

Also Known as AM

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11535

Summary

Predicted to enable Adrenomedullin receptor binding activity. Involved in several processes, including negative regulation of vascular permeability; positive regulation of vasculogenesis; and vascular associated smooth muscle cell development. Acts upstream of or within several processes, including chordate embryonic development; heart development; and positive regulation of cell population proliferation. Predicted to be located in cytoplasm and extracellular space. Is expressed in several structures, including cardiovascular system; extraembryonic component; gut; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in brain infarction; breast cancer; pancreatic cancer; and pulmonary hypertension. Orthologous to human ADM (Adrenomedullin). [provided by Alliance of Genome Resources, Apr 2022]

Adm Products (1)

mRNA Protein Name
NM_009627.2 NP_033757.1 pro-adrenomedullin precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within branching involved in labyrinthine layer morphogenesis IMP
IMP: Inferred from mutant phenotype
16981008 MGI
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
16537897 MGI
acts upstream of or within developmental growth IMP
IMP: Inferred from mutant phenotype
16981008 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
16537897 MGI
involved in heart development IMP
IMP: Inferred from mutant phenotype
18097473 MGI
involved in negative regulation of vascular permeability IMP
IMP: Inferred from mutant phenotype
18097473 MGI
acts upstream of or within neural tube closure IMP
IMP: Inferred from mutant phenotype
16981008 MGI
involved in positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
18097473 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
16537897 MGI
involved in positive regulation of vasculogenesis IMP
IMP: Inferred from mutant phenotype
18097473 MGI
acts upstream of or within spongiotrophoblast layer development IMP
IMP: Inferred from mutant phenotype
16981008 MGI
involved in vascular associated smooth muscle cell development IMP
IMP: Inferred from mutant phenotype
18097473 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pro-adrenomedullin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0876 Arenobufagin Inducer 99.82% Unkown
HY-124277 ADM 12 Antagonist 98.86% Unkown
HY-N1514 Ganoderenic acid B 99.95% Unkown
HY-P1838 Proadrenomedullin (45-92), human 99.77% Unkown
HY-P3919A Adrenotensin (human) TFA 99.09% Unkown
HY-RS00386 ADM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-178349 P-gp inhibitor 30 / Unkown
HY-P3919 Adrenotensin (human) / Unkown
HY-RS00387 ADM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00388 ADM5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16948 Adm Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20246 Adm2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23391 Adm Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26754 Adm2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adm NCBI NCBI:133