2. Gene
  3. RAB3C - RAB3C, member RAS oncogene family Gene

RAB3C - RAB3C, member RAS oncogene family Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 115827 | Gene type: protein coding

About RAB3C

Cytogenetic location: 5q11.2 Genomic coordinates (GRCh38): 5:58,582,152-58,859,394 (from NCBI)

This gene has 4 transcripts (splice variants), 220 orthologues and 68 paralogues. Biased expression in brain (RPKM 24.5) and adrenal (RPKM 6.1).

Summary

This gene is a member of the Ras oncogene family and encodes a small GTPase. Other similar small GTPases are known to be involved in vesicle trafficking, and the encoded protein was shown to play a role in recycling phagocytosed MHC class 1 complexes to the cell surface. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

RAB3C Products(2)

mRNA Protein Name
NM_001317915.2 NP_001304844.1 ras-related protein Rab-3C isoform 2
NM_138453.4 NP_612462.1 ras-related protein Rab-3C isoform 1

RAB3C Protein Structure

Ras

Ras: Ras family (32 - 191)

  • 0
  • 100
  • 200
  • 227 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-3C

Related Diseases

Diseases Alias
Warburg Micro Syndrome 1

Warburg Micro Syndrome

Micro Syndrome

Warbm

WARBM1

Warburg Sjo Fledelius Syndrome

Warburg-Sjo-Fledelius Syndrome

Micro Syndrome 1

Microcephaly, Microcornea, Congenital Cataract, Intellectual Disability, Optic Atrophy And Hypogenitalism
Focal Epithelial Hyperplasia

Heck'S Disease

Heck Disease

Multifocal Epithelial Hyperplasia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11557 RAB3C Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus RAB3C VGNC VGNC:97591
Rattus norvegicus RAB3C RGD RGD:620923
Mus musculus RAB3C MGD MGI:1914545
Canis familiaris RAB3C VGNC VGNC:45284
Bos taurus RAB3C VGNC VGNC:33651
Macaca mulatta RAB3C VGNC VGNC:81541