Alcam - activated leukocyte cell adhesion molecule Gene

Also Known as BEN; SC1; MuSC; CD166; DM-GRASP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11658

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within motor neuron axon guidance. Located in axon; external side of plasma membrane; and neuronal cell body. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and vibrissa. Orthologous to human ALCAM (activated leukocyte cell adhesion molecule). [provided by Alliance of Genome Resources, Apr 2022]

Alcam Products (2)

mRNA Protein Name
NM_001331110.1 NP_001318039.1 CD166 antigen isoform 2 precursor
NM_009655.3 NP_033785.1 CD166 antigen isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9209500 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within axon guidance IMP
IMP: Inferred from mutant phenotype
15345243 MGI
acts upstream of or within motor neuron axon guidance IMP
IMP: Inferred from mutant phenotype
15345243 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
16267219 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
9209500 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
16267219 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CD166 antigen

Recombinant Alcam Proteins

Cat. No. Product Name Accession Purity
HY-P7472 ALCAM/CD166 Protein, Mouse (HEK293, Fc) Q61490 (W28-K527) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P78058 ALCAM/CD166 Protein, Mouse (Biotinylated, HEK293, His-Avi) Q61490 (W28-K527) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P78236 ALCAM/CD166 Protein, Mouse (HEK293, His) Q61490 (W28-K527) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00557 ALCAM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17128 Alcam Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23573 Alcam Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99788 Praluzatamab Inhibitor 99.14% Unkown
HY-P991532 AT002 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Alcam NCBI NCBI:214