Khdrbs1 - KH RNA binding domain containing, signal transduction associated 1 Gene

Also Known as P62; Sam68

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117268

Summary

Enables SH3 domain binding activity and identical protein binding activity. Involved in cell surface receptor signaling pathway; regulation of alternative mRNA splicing, via spliceosome; and spermatogenesis. Located in cytoplasm; membrane; and nucleus. Part of Grb2-Sos complex. Orthologous to human KHDRBS1 (KH RNA binding domain containing, signal transduction associated 1). [provided by Alliance of Genome Resources, Apr 2022]

Khdrbs1 Products (1)

mRNA Protein Name
NM_130405.2 NP_569089.1 KH domain-containing, RNA-binding, signal transduction-associated protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SH3 domain binding IDA
IDA: Inferred from direct assay
12112020 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
15345239 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10437794 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
12112020 RGD
Biological Process GO Annotation Evidence References Source
involved in cell surface receptor signaling pathway IDA
IDA: Inferred from direct assay
10437794 RGD
involved in regulation of alternative mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
15345239 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
10332027 RGD
Cellular Component GO Annotation Evidence References Source
part of Grb2-Sos complex IDA
IDA: Inferred from direct assay
12112020 RGD
located in nucleus IDA
IDA: Inferred from direct assay
10332027 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

KH domain-containing, RNA-binding, signal transduction-associated protein 1

  • GAP-associated tyrosine phosphoprotein p62

  • KH domain containing, RNA binding, signal transduction associated 1

  • KH domain-containing, RNA-binding, signal transduction-associated protein 1-like

  • p21 Ras GTPase-activating protein-associated p62

  • p68

  • src a

Khdrbs1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Khdrbs1 Q91V33 Pik3r1 Rattus norvegicus Q63787
CoIP
10437794
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07237 KHDRBS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Khdrbs1 NCBI NCBI:10657