BORCS5 - BLOC-1 related complex subunit 5 Gene
Also Known as LOH12CR1; LOH1CR12
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 118426
Summary
Involved in lysosome localization and organelle transport along microtubule. Located in cytoplasmic side of lysosomal membrane and plus-end Kinesin complex. Part of BORC complex. Implicated in colorectal adenocarcinoma. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in brain (RPKM 2.1), bone marrow (RPKM 1.5) and 25 other tissues.
BORCS5 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001300742.3 | NP_001287671.1 | BLOC-1-related complex subunit 5 isoform 2 |
| NM_001330356.2 | NP_001317285.1 | BLOC-1-related complex subunit 5 isoform 3 |
| NM_058169.6 | NP_477517.1 | BLOC-1-related complex subunit 5 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
16189514 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in lysosome localization |
IMP
IMP: Inferred from mutant phenotype
|
25898167 | GOA |
| involved in organelle transport along microtubule |
IMP
IMP: Inferred from mutant phenotype
|
25898167 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of BORC complex |
IDA
IDA: Inferred from direct assay
|
25898167 | GOA |
| part of BORC complex |
IPI
IPI: Inferred from physical interaction
|
25898167 | GOA |
| located in cytoplasmic side of lysosomal membrane |
IMP
IMP: Inferred from mutant phenotype
|
25898167 | GOA |
| located in membrane |
IMP
IMP: Inferred from mutant phenotype
|
25898167 | GOA |
| part of plus-end kinesin complex |
IDA
IDA: Inferred from direct assay
|
25898167 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service
BORCS5 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
BORCS5 | Q969J3 | CCDC196 | Homo sapiens | A0A1B0GWI1 | 32296183 | |
|
Intra
|
BORCS5 | Q969J3 | CCDC196 | Homo sapiens | A0A1B0GWI1 | 32296183 | |
|
Intra
|
BORCS5 | Q969J3 | PUF60 | Homo sapiens | Q9UHX1 | 25416956 | |
|
Intra
|
BORCS5 | Q969J3 | PUF60 | Homo sapiens | Q9UHX1 | 25416956 | |
|
Intra
|
BORCS5 | Q969J3 | PUF60 | Homo sapiens | Q9UHX1 | 25416956 |
Cross: Cross-species interaction
Intra: Intraspecies interaction