PIK3AP1 - phosphoinositide-3-kinase adaptor protein 1 Gene

Homo sapiens

Also known as BCAP

Gene ID: 118788 | Gene type: protein coding

About PIK3AP1

Cytogenetic location: 10q24.1 Genomic coordinates (GRCh38): 10:96,593,315-96,720,514 (from NCBI)

This gene has 6 transcripts (splice variants), 199 orthologues and 1 paralogue. Broad expression in spleen (RPKM 34.0), lymph node (RPKM 33.6) and 19 other tissues.

Summary

Predicted to enable phosphatidylinositol 3-kinase regulatory subunit binding activity and signaling receptor binding activity. Predicted to be involved in regulation of inflammatory response; regulation of signal transduction; and Toll-like Receptor signaling pathway. Predicted to be located in cytoplasm and membrane. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

PIK3AP1 Products(1)

mRNA	Protein	Name
NM_152309.3	NP_689522.2	phosphoinositide 3-kinase adapter protein 1

PIK3AP1 Protein Structure

DBB

0
200
400
600
805 a.a.

Protein Preferred Names

Protein Names

phosphoinositide 3-kinase adapter protein 1

B cell adaptor protein

Related Diseases

Diseases

Alias

Pharyngitis

Acute Pharyngitis	Chronic Pharyngitis
Acute Sore Throat	Chronic Sore Throat
Persistent Sore Throat	Pharyngeal Diseases
Chronic Pharyn/Nasopharyngitis	Chronic Pharyngitis And Nasopharyngitis
Inflamed Throat	Pharyngeal Disease
Pharyngeal Disorder	Pharyngitis - Acute
Sore Throat - Chronic	Acute Pharyngitis Nos
Acute Sore Throat Nos	Acute Throat Inflammation
Infective Pharyngitis	Infection Of Pharynx
Acute Infective Pharyngitis	Acute Infective Pharyngitis Nos
Acute Pharyngeal Inflammation	Inflammation Of The Throat
Throat Inflammation	Throat Infection
Putrid Pharyngitis	Pharyngeal Inflammation
Pharyngitis Nos	Chronic Throat Pain
Throat Catarrh

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10510	PIK3AP1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	PIK3AP1	VGNC	VGNC:64176
Bos taurus	PIK3AP1	VGNC	VGNC:54469
Macaca mulatta	PIK3AP1	VGNC	VGNC:75891
Mus musculus	PIK3AP1	MGD	MGI:1933177
Canis familiaris	PIK3AP1	VGNC	VGNC:44550
Rattus norvegicus	PIK3AP1	RGD	RGD:1307744

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