Bach1 - BTB and CNC homology 1, basic leucine zipper transcription factor 1 Gene

Also Known as 6230421P05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12013

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Orthologous to human BACH1 (BTB domain and CNC homolog 1). [provided by Alliance of Genome Resources, Apr 2022]

Bach1 Products (1)

mRNA Protein Name
NM_007520.2 NP_031546.1 transcription regulator protein BACH1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
8887638 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
8887638 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
8887638 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
8887638 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
8887638 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8887638 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8887638 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8887638 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
8887638 MGI
involved in regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
19170764 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
8887638 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription regulator protein BACH1

  • BTB and CNC homolog 1

  • BTB and CNC homology 1 transcription factor

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-167874 ASP-8731 Inhibitor 98.42% Phase 1

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153040 HPPE Inhibitor 99.71% Unkown
HY-111827 S-1-Propenyl-L-cysteine 99.91% Unkown
HY-RS01339 BACH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-17655 TBE56 Inhibitor / Unkown
HY-RS01623 BRIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17026 Bach1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20866 Brip1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23469 Bach1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bach1 NCBI NCBI:571