GPHB5 - glycoprotein hormone subunit beta 5 Gene

Also Known as B5; GPB5; ZLUT1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 122876

Summary

GPHB5 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002 [PubMed 12089349]).[supplied by OMIM, Mar 2008]
Low expression observed in reference dataset.

GPHB5 Products (1)

mRNA Protein Name
NM_145171.4 NP_660154.3 glycoprotein hormone beta-5 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12045258 GOA
enables protein heterodimerization activity IDA
IDA: Inferred from direct assay
12045258 GOA
enables thyrotropin-releasing hormone receptor binding IMP
IMP: Inferred from mutant phenotype
12045258 GOA
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
12045258 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPHB5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GPHB5 Q86YW7 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra
GPHB5 Q86YW7 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra
GPHB5 Q86YW7 GPHA2 Homo sapiens Q96T91
GMS
12045258
Intra
GPHB5 Q86YW7 GPHA2 Homo sapiens Q96T91
Crosslink
12045258
Intra
GPHB5 Q86YW7 GPHA2 Homo sapiens Q96T91
Y2H
12045258
Intra
GPHB5 Q86YW7 TMEM179B Homo sapiens Q7Z7N9
Y2H Prey Pooling
32296183
Intra
GPHB5 Q86YW7 TMEM179B Homo sapiens Q7Z7N9
Y2H Array
32296183
Intra
GPHB5 Q86YW7 CIMIP2B Homo sapiens A8MTA8-2
Y2H Array
32296183
Intra
GPHB5 Q86YW7 CIMIP2B Homo sapiens A8MTA8-2
Y2H Prey Pooling
32296183
Intra
GPHB5 Q86YW7 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra
GPHB5 Q86YW7 SSMEM1 Homo sapiens Q8WWF3
Validated Y2H
32296183
Intra
GPHB5 Q86YW7 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra
GPHB5 Q86YW7 ERVFRD-1 Homo sapiens P60508
Y2H Prey Pooling
32296183
Intra
GPHB5 Q86YW7 ERVFRD-1 Homo sapiens P60508
Y2H Array
32296183
Intra
GPHB5 Q86YW7 TEX29 Homo sapiens Q8N6K0
Validated Y2H
32296183
Intra
GPHB5 Q86YW7 TEX29 Homo sapiens Q8N6K0
Y2H Array
32296183
Intra
GPHB5 Q86YW7 TEX29 Homo sapiens Q8N6K0
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction